Arixtra fondaparinux sodium side effects, images, uses. Arixtra fondaparinux sodium injection, solution arixtra 25. Dificid fidaxomicin is considered medically necessary. Arixtra fondaparinux is effective at treating blood clots in the extremeties and those that have travelled to the lungs. Administration of arixtra earlier than 6 hours after surgery increases the risk of major bleeding. Read the patient information leaflet if available from your pharmacist before you start using fondaparinux and each time you get a refill. However, you may be sent home with this medication, in which case you or a caregiver must administer the injections. Fondaparinux package insert pdf the recommended dose of fondaparinux is mg once daily administered instruction for selfadministration is mentioned in the package leaflet. This site is intended for us healthcare professionals only. This emedtv page lists important arixtra warnings and precautions, including potentially serious side effects and possible drug interactions. Weighing the options for anticoagulation in obesity caitlin s.
Drugs az pill identifier supplements symptom checker diseases dictionary media. Use of fondaparinux arixtra in acute coronary syndrome. We aim to help each and every american in that situation. This treatment replaces enoxaparin 1mgkg twice daily.
Discard product if it contains particulate matter, is cloudy, or discolored do not freeze. One potential advantage of fondaparinux over lmwh or unfractionated heparin. As this emedtv web resource discusses, arixtra is an injection used to help prevent and treat blood clots. Jun 30, 2019 fondaparinux package insert pdf the recommended dose of fondaparinux is mg once daily administered instruction for selfadministration is mentioned in the package leaflet. The needle protection system of the arixtra prefilled syringes have been designed with a. Arixtra, innfondaparinux sodium european commission. Apr 28, 2019 acetadote package insert pdf official website of iv acetadote acetylcysteine. Mylan manufactures arixtra fondaparinux sodium injection, solution arixtra in strengths of 25 mg05 ml 5 mgml5 mg04 ml 125 mgml75 mg06 ml 125 mgml10 mg08 ml 125 mgml. If you are in a hospital, a healthcare provider will probably administer the injection. Please read this leaflet carefully before you start using arixtra. Overdose your doctor or pharmacist has information on how to recognise and treat an overdose. Dosing and adverse effects view in chinese fondaparinux arixtra is a synthetic anticoagulant based on the pentasaccharide sequence that makes up the minimal antithrombin at binding region of heparin. What should i discuss with my healthcare provider before using fondaparinux arixtra.
Prevention of dvt may prevent development of pulmonary embolism in these patients. Arixtra fondaparinux is a safe option for use in patients who have experienced a rare, lifethreatening reaction to another anticoagulant, heparin. Do not administer arixtra as prophylactic therapy for patients undergoing hip fracture, hip replacement, or knee replacement surgery and abdominal surgery see contraindications 4. Arixtra fondaparinux is used to prevent a type of blood clot called deep vein thrombosis dvt, which can lead to blood clots in the lungs pulmonary embolism. Reproductive and developmental toxicity studies performed in rats at oral doses up to 6. The usual duration of administration is 7 to 10 days see clinical studies 14. Administer the initial dose 12 3 hours prior to surgery. Nov 09, 2018 arixtra fondaparinux is used to prevent a type of blood clot called deep vein thrombosis dvt, which can lead to blood clots in the lungs pulmonary embolism. Arixtra injection is provided in a singledose, prefilled syringe affixed with an automatic needle protection system. Clexane is one of a group of medicines called low molecular weight heparins lmwh. Arixtra injection is available in the following strengths and package sizes.
Fragmin dalteparin sodium injection for subcutaneous. No dosage reduction is required for patients with mild renal impairment creatinine clearance 50 mlmin. Fondaparinux sodium injection is provided in a singledose, prefilled syringe affixed with an active needle protection system. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Mar 03, 2019 dificid package insert pdf view the savings offer for dificid fidaxomicin. The safety and efficacy of prophylactic doses of lovenox in obese patients bmi 30 kgm 2 has not. Jan 17, 2020 fondaparinux sodium injection is available in the following strengths and package sizes. Instructions on how to use the arixtra syringe are contained in the package insert in each arixtra carton. Apr 25, 2019 argatroban package insert pdf store in original package until time of use. Fondaparinux is used to prevent deep vein thrombosis, a condition in which harmful blood clots form in the blood vessels of the legs.
Dailymed arixtra fondaparinux sodium injection, solution. May, 2019 belimumab package insert pdf belimumab has been studied in a limited number of sle patients with renal syringe are provided at the end of the package leaflet see stepbystep. Fidaxomicin is a topically acting drug that cannot be used to treat systemic infections. This medicine is used for several days after hip fracture surgery, hip or knee replacement surgery, and in some cases. Some medicines and arixtra may interfere with each other. These blood clots can travel to the lungs and can become lodged in the blood vessels of the lungs, causing a condition called pulmonary embolism. Do not use clexane after the expiry date printed on the syringe or ampoule. Dosing recommendations for patients with a crcl 30 mlmin, the recommended dose of pr adaxa is 150 mg taken orally, twice daily, after 510 days of parenteral anticoagulation. Fondaparinux sodium is administered by subcutaneous injection.
Fondaparinux trade name arixtra is an anticoagulant medication chemically related to low. Argatroban package insert pdf store in original package until time of use. Dosage of fondaparinux sodium is expressed in terms of the salt. Arixtra, innfondaparinux sodium european medicines agency. Arixtra package insert pdf instruction for selfadministration is mentioned in the package leaflet. Side effects of arixtra fondaparinux sodium, warnings, uses rxlist. There are over 100 million americans that either cant afford their medication or are struggling to afford their medication.
See full prescribing information for complete boxed. Arixtra fondaparinux sodium injection usp qualitative and. The needle protection system of the arixtra prefilled syringe has been designed with an. Easy to read fda package insert, drug facts, dosage and administration, and adverse effects for arixtra fondaparinux skip to. A dose of lovenox of 40 mg once a day subcutaneously may be considered for hip replacement surgery for up to 3 weeks. Your doctor may have prescribed clexane for another reason. Do not use clexane if the packaging is torn or shows signs of tampering. Arixtra should be used with caution in elderly patients as renal function decreases with age see renal impairment, warnings and precautions. Arixtra will normally be stored in the pharmacy or on the hospital ward. Arixtra fondaparinux side effects, dosage, interactions. Ask your doctor or pharmacist if you have any concerns. Lovenox is indicated for the prophylaxis of ischemic complications of unstable angina and nonqwave myocardial infarction, when concurrently administered with aspirin. Each singledose, prefilled syringe of arixtra, affixed with an automatic needle protection system, contains 2.
Arixtra is increased in adults who weigh pdf the recommended dose of fondaparinux is mg once daily administered instruction for selfadministration is mentioned in. Arixtra syringe are contained in the package insert in each arixtra carton. This medication may not be safe for people with certain medical conditions, such as a bleeding disorder, high blood pressure, or an aneurysm. Medical patients during acute illness the recommended dose of lovenox is 40 mg once a day administered by subcutaneous injection for. May, 2019 arixtra prescribing information pdf posted on may, 2019 by admin gsk has halted all shipments of arixtra starter kits containing the triad for important product information, log onto arixtra mg ml solution for injection, prefilled syringe.
Administer the initial dose no earlier than 6 to 8 hours after surgery. Drug industry documents archive glaxosmithkline prize side effects. Adjust the timing of the dose on postoperative day 1 accordingly. In patients undergoing surgery, the timing of the first dose of arixtra requires strict adherence see warnings and precautions. Individuals using assistive technology may not be able to fully access the information contained in this file. The safety and effectiveness of clexane has not been established in children. Learn about drug imprint, side effects, uses treating, dosage, interaction, overdose, and warnings. Ask your doctor if you have any questions about why clexane has been prescribed for you. Fondaparinux arixtra is a chemically synthesized version of the active pentasaccharide subunit of heparin that. Jan 23, 2012 arixtra increases the risk for bleeding in patients who weigh less than 50 kg, compared to patients with higher weights. The package insert should be consulted in such cases to determine the recommended dose. Because arixtra is a brandname drug, it can be very expensive. It is also used to treat existing blood clots in the lungs or in the veins.
Optimal timing between administration of fondaparinux and neuraxial procedures. This page offers more information on this prescription blood thinner, including tips on how to give yourself these injections safely. Arixtra fondaparinux dosing, indications, interactions. Arixtra fondaparinux sodium injection usp qualitative and quantitative composition each prefilled syringe contains 2. Laboratory monitoring of fondaparinux is possible by utilizing factor xa inhibitory activity of the drug. Jan 20, 2019 amaryl lids to download pdf you need some things, like my website and the name of the file. What are the possible side effects of fondaparinux arixtra.
Print an instant ps card now, and use it as a arixtra discount card to get a cheap arixtra price. Antixa assay used for monitoring heparin is modified by. Read all of this leaflet carefully before you start using. Trademarks are owned by or licensed to the gsk group of companies. Arixtra fda prescribing information, side effects and uses. Fondaparinux arixtra is a chemically synthesized version of. Aranesp package insert pdf throughout this section of the package insert, the aranesp study numbers in 2 openlabel studies, aranesp or epoetin alfa were administered for the. These medicines work by reducing blood clotting activity. Arixtra fondaparinux is used after knee, hip, or abdominal surgeries to prevent blood clotting. Feb 18, 2020 arixtra is supplied as a sterile, preservativefree injectable solution for subcutaneous use. If you think that you or anyone else may have been given too much arixtra, immediately telephone your doctor or contact. Amaryl lids to download pdf you need some things, like my website and the name of the file. If you are not sure whether you should start using clexane, talk to your doctor or. What is the most important information i should know about fondaparinux arixtra.
You may not be able to use arixtra safely if you weigh less than 110 pounds or have severe kidney problems. Weighing the options for anticoagulation in obesity. Use the leg or abdominal wall, alternating sites daily. The fda approved the agent in 2001 with a 1p rating. Eligible, privately insured patients may save on a qualifying prescription with the savings coupon for. Highlights of prescribing information these highlights do not include all the information needed to use coumadin safely and effectively. Find patient medical information for arixtra subcutaneous on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. This page contains brief information about palifermin and a collection of links to more information about the use of this drug, research results. Arixtra is intended for use under a physicians guidance. You are encouraged to report vaccine adverse events to the us department of health and human services. The usual duration of administration of arixtra is 5 to 9 days.
Fondaparinux is used after knee, hip, or abdominal surgeries to prevent blood clotting. Dec 01, 2019 arixtra fondaparinux sodium injection, usp is available in the following strengths. Individuals using assistive technology may not be able to. Do not use arixtra if the packaging is torn or shows signs of tampering. It must not be administered by intramuscular injection.
Create a skin fold between the thumb and forefinger, insert the whole length of the needle at a 90 degree angle and administer the whole contents of the syringe. Fondaparinux sodium injection is intended for use under a physicians guidance. Instruction for selfadministration is mentioned in the package leaflet. Find informantion about acetadote and acetaminophen overdose, a dosage calculator, emergency facility. Continue treatment with arixtra for at least 5 days and until a therapeutic oral anticoagulant effect is established inr 2 to 3. In the prevention of vtes, the recommended dose of arixtra is 2. Fragmin dalteparin sodium injection for subcutaneous use. Successful use of fondaparinux as an alternative anticoagulant in a 2monthold infant letter pediatr blood cancer.